Results: Phytochemical tests showed presence of different kinds of phyto-constituents in aqueous, ether and methanol extract of Stevia rebaudiana leaves. Diabetes was induced by a single dose of 5% alloxan monohydrate (125 mg/kg, i.p.) after 24 hour fasting.Blood samples were analysed on day 0, 1, 5, 7, 14 and 28. rebaudiana rats were divided into seven groups (n = 6). For the study of antidiabetic effect of S. aqueous extract (Group II), ether extract (Group III) and methanolic extract (Group IV). Acute and sub-acute toxicity were conducted on twenty four Albino rats, divided into one control (Group I) and three treatment groups viz. Methods: Preliminary phytochemical screening of aqueous, ether and methanolic extracts of S. Other studies have shown that it has antibacterial as well as antiviral property. Submitted: 07-04-2010 Revised: 02-08-10 Published: 07-09-2010īackground: Stevia rebaudiana regulates blood sugar, prevents hypertension and tooth decay. College of Pharmacy, Moga - 142 001, Punjab, 2Department of Veterinary Pathology, College of Veterinary Science and A.H., Birsa Agricultural University, Ranchi - 834 006, India Royĭepartment of Pharmacology and Toxicology, College of Veterinary Science and A.H., Birsa Agricultural University, Ranchi - 834 006, Department of Pharmacology, I.S.F. Kujur, Vishakha Singh, Mahendra Ram, Harlokesh Narayan Yadava1, K. Antidiabetic activity and phytochemical screening of crude extract of Stevia rebaudiana in alloxan-induced diabetic rats
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